FMOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID

FMOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID - Names and Identifiers

Name	Fmoc-L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid
Synonyms	FMOC-L-TPI FMOC-TPI-OH Fmoc-L-Tpi-OH FMOC-THNH(3)-OH RARECHEM BK PT 0090 Fmoc-L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid FMOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID (S)-2-FMOC-1,2,3,4-TETRAHYDRONORHARMANE-3-CARBOXYLIC ACID N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-TRYPTOLINE-3-CARBOXYLIC ACID N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-1,2,3,4-TETRAHYDRONORHAM-3-CARBOXYLIC ACID (3S)-2-[(9H-fluoren-9-ylmethoxy)carbonyl]-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid
CAS	204322-23-6
InChI	InChI=1/C27H22N2O4/c30-26(31)25-13-21-20-11-5-6-12-23(20)28-24(21)14-29(25)27(32)33-15-22-18-9-3-1-7-16(18)17-8-2-4-10-19(17)22/h1-12,22,25,28H,13-15H2,(H,30,31)/t25-/m0/s1

FMOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID - Physico-chemical Properties

Molecular Formula	C27H22N2O4
Molar Mass	438.47
Density	1.396±0.06 g/cm3(Predicted)
Boling Point	702.4±60.0 °C(Predicted)
Flash Point	378.6°C
Vapor Presure	1.04E-20mmHg at 25°C
pKa	3.92±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.713

FMOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3
HS Code	29242990
Hazard Class	IRRITANT

FMOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID - Introduction

Fmoc-L-1,2,3, acid is an organic compound. The following will introduce its nature, use, preparation and safety information.

1. Nature:
Fmoc-L-1,2,3, acid is a solid powder with white or almost white color. Its molecular formula is C22H25NO4 and its molecular weight is 367.44g/mol. It is a photosensitive compound, soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane and N,N-dimethylacetamide (DMF), but insoluble in water.

2. Use:
Fmoc-L-1,2,3, acid is a commonly used protecting group reagent, mainly used for solid phase synthesis and peptide synthesis process of protecting group removal. It can react with amino acid or amino group in peptide segment by acylation reaction to form Fmoc protecting group with protective effect.

3. Preparation method:
Fmoc-L-1,2,3, acid is usually obtained by chemical synthesis. The specific preparation method can refer to the relevant literature.

4. Safety Information:
Fmoc-L-1,2,3, acid is generally relatively safe under normal operating conditions. However, since it is a chemical agent, appropriate protective measures need to be taken. Wear appropriate protective gloves and goggles during operation to avoid contact with skin, eyes and inhalation of dust. During storage, it should be kept in a dry, cool place, away from open flames and heat sources. At the same time, it is also necessary to strictly follow the relevant safety operation procedures. In case of accidental contact or aspiration, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15